Coagulation/Complement Activation and Cerebral Hypoperfusion in Relapsing-Remitting Multiple Sclerosis

IntroductionMultiple sclerosis (MS) is a demyelinating disease of the central nervous system with an underlying immune-mediated and inflammatory pathogenesis. Innate immunity, in addition to the adaptive immune system, plays a relevant role in MS pathogenesis. It represents the immediate non-specifi...

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Main Authors: Tatiana Koudriavtseva, Annunziata Stefanile, Marco Fiorelli, Caterina Lapucci, Svetlana Lorenzano, Silvana Zannino, Laura Conti, Giovanna D’Agosto, Fulvia Pimpinelli, Enea Gino Di Domenico, Chiara Mandoj, Diana Giannarelli, Sara Donzelli, Giovanni Blandino, Marco Salvetti, Matilde Inglese
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2020.548604/full