Cellular fatty acid synthase is required for late stages of HIV-1 replication

Cellular fatty acid synthase is required for late stages of HIV-1 replication

Abstract Background Like all viruses, HIV-1 relies on host systems to replicate. The human purinome consists of approximately two thousand proteins that bind and use purines such as ATP, NADH, and NADPH. By virtue of their purine binding pockets, purinome proteins are highly druggable, and many exis...

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Bibliographic Details
Main Authors: Manjusha M. Kulkarni, Annette N. Ratcliff, Menakshi Bhat, Yazan Alwarawrah, Philip Hughes, Jesus Arcos, David Loiselle, Jordi B. Torrelles, Nicholas T. Funderburg, Timothy A. Haystead, Jesse J. Kwiek
Format: Article
Language:English
Published: BMC 2017-09-01
Series:Retrovirology
Subjects:
Human immunodeficiency virus type 1
Host-virus interaction
Fatty acid synthase
Antiviral pharmacology
Fasnall
Online Access:http://link.springer.com/article/10.1186/s12977-017-0368-z

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http://link.springer.com/article/10.1186/s12977-017-0368-z

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