Knockdown of circDENND4C inhibits glycolysis, migration and invasion by up-regulating miR-200b/c in breast cancer under hypoxia

Knockdown of circDENND4C inhibits glycolysis, migration and invasion by up-regulating miR-200b/c in breast cancer under hypoxia

Abstract Background Hypoxia is a key feature of breast cancer, which affects cancer development, metastasis and metabolism. Previous studies suggested that circular RNAs (circRNAs) could participate in cancer progression and hypoxia regulation. This study aimed to investigate the role of circRNA dif...

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Bibliographic Details
Main Authors: Shasha Ren, Jiuzhou Liu, Yun Feng, Zhenyu Li, Liang He, Leilei Li, Xiaozhong Cao, Zhenghua Wang, Yanwu Zhang
Format: Article
Language:English
Published: BMC 2019-09-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Breast cancer
circDENND4C
miR-200b
miR-200c
Glycolysis
Migration
Online Access:http://link.springer.com/article/10.1186/s13046-019-1398-2

Internet

http://link.springer.com/article/10.1186/s13046-019-1398-2

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