Nutritional and Pharmacological Strategies to Regulate Microglial Polarization in Cognitive Aging and Alzheimer’s Disease

Nutritional and Pharmacological Strategies to Regulate Microglial Polarization in Cognitive Aging and Alzheimer’s Disease

The study of microglia, the immune cells of the brain, has experienced a renaissance after the discovery of microglia polarization. In fact, the concept that activated microglia can shift into the M1 pro-inflammatory or M2 neuroprotective phenotypes, depending on brain microenvironment, has complete...

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Bibliographic Details
Main Authors: Emiliano Peña-Altamira, Sabrina Petralla, Francesca Massenzio, Marco Virgili, Maria L. Bolognesi, Barbara Monti
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-06-01
Series:Frontiers in Aging Neuroscience
Subjects:
immunomodulation
microglia
cognitive impairment
aging
Alzheimer’s disease
drug therapy
Online Access:http://journal.frontiersin.org/article/10.3389/fnagi.2017.00175/full

Internet

http://journal.frontiersin.org/article/10.3389/fnagi.2017.00175/full

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