Assessing the immunogenicity and toxicity of the AFPL1-conjugate nicotine vaccine using heterologous and homologous vaccination routes.

Despite the increased risks of cancers and cardiovascular related diseases, tobacco smoking continues to be prevalent in the population due largely in part to the addictive nature of nicotine. Nicotine vaccines are an attractive alternative to the current smoking cessation options but have yet to be...

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Bibliographic Details
Main Authors: Nya L Fraleigh, Reynaldo Oliva, Jordan D Lewicky, Alexandrine L Martel, Reinaldo Acevedo, García-Rivera Dagmar, Hoang-Thanh Le
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0221708