Synergistic effects of vorinostat (SAHA) and azoles against Aspergillus species and their biofilms

Abstract Background Invasive aspergillosis is a fungal infection that occurs mainly in immunocompromised patients. It is responsible for a high degree of mortality and is invariably unresponsive to conventional antifungal treatments. Histone deacetylase inhibitors can affect the cell cycle, apoptosi...

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Bibliographic Details
Main Authors: Bo Tu, Gendi Yin, Hui Li
Format: Article
Language:English
Published: BMC 2020-02-01
Series:BMC Microbiology
Subjects:
Online Access:https://doi.org/10.1186/s12866-020-1718-x