Development of a Novel Method for Determination of 11 Antiretroviral Drugs Concentrations in Human Plasma by Ultra-Performance Liquid Chromato- graphy-Photodiode Array Detection Method

Development of a Novel Method for Determination of 11 Antiretroviral Drugs Concentrations in Human Plasma by Ultra-Performance Liquid Chromato- graphy-Photodiode Array Detection Method

Objective: To develop ultra-performance liquid chromatography-photodiode array detection (UPLC-PDA) method that is fully validated for measuring 11 antiretroviral drugs concentrations in human plasma. Methods: Chromatographic separation was performed on an ACQUITY UPLCTM BEH Shield RP, 1.7 μm (100...

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Bibliographic Details
Main Authors: Rasda Boonprasert, M.Sc., Raveewan Klintip, M.Sc., Supawadee Phakdeenukoolkijja, M.Sc, Winai Ratanasuwan, M.D., Teera Kolladarungkri, M.D.
Format: Article
Language:English
Published: Mahidol University 2018-05-01
Series:Siriraj Medical Journal
Subjects:
UPLC/PDA
antiretroviral
therapeutic drug monitoring
(Siriraj Med J 2018;70: 238-246)
Online Access:http://www.smj.si.mahidol.ac.th/sirirajmedj/index.php/smj/article/view/2581/2583

Internet

http://www.smj.si.mahidol.ac.th/sirirajmedj/index.php/smj/article/view/2581/2583

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