High-throughput high-resolution class I HLA genotyping in East Africa.

HLA, the most genetically diverse loci in the human genome, play a crucial role in host-pathogen interaction by mediating innate and adaptive cellular immune responses. A vast number of infectious diseases affect East Africa, including HIV/AIDS, malaria, and tuberculosis, but the HLA genetic diversi...

Full description

Bibliographic Details
Main Authors: Rebecca N Koehler, Anne M Walsh, Eric E Sanders-Buell, Leigh Anne Eller, Michael Eller, Jeffrey R Currier, Christian T Bautista, Fred Wabwire-Mangen, Michael Hoelscher, Leonard Maboko, Jerome Kim, Nelson L Michael, Merlin L Robb, Francine E McCutchan, Gustavo H Kijak
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2873994?pdf=render