QKI 6 ameliorates CIRI through promoting synthesis of triglyceride in neuron and inhibiting neuronal apoptosis associated with SIRT1‐PPARγ‐PGC‐1α axis

QKI 6 ameliorates CIRI through promoting synthesis of triglyceride in neuron and inhibiting neuronal apoptosis associated with SIRT1‐PPARγ‐PGC‐1α axis

Abstract Background The stroke induced by ischemia of brain remains high incidence and death rate. The study wanted to confirm the effects of Quaking 6 (QKI 6) on the protection role in neurons of rat model of cerebral ischemia/reperfusion injury (CIRI). Material and methods The rat model with CIRI...

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Bibliographic Details
Main Authors: Rui Liu, Hongzeng Li, Jingyuan Deng, Qunqiang Wu, Chunhua Liao, Qun Xiao, Qi Chang
Format: Article
Language:English
Published: Wiley 2021-08-01
Series:Brain and Behavior
Subjects:
cerebral ischemia/reperfusion injury
middle cerebral artery occlusion
neuronal apoptosis
Quaking 6
sirtuin 1
synthesis of triglyceride
Online Access:https://doi.org/10.1002/brb3.2271

Internet

https://doi.org/10.1002/brb3.2271

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