Polydeoxyribonucleotide Exerts Therapeutic Effect by Increasing VEGF and Inhibiting Inflammatory Cytokines in Ischemic Colitis Rats

Ischemic colitis is resulted from an inadequate blood supply to a segment or entire colon. Polydeoxyribonucleotide (PDRN), extracted from salmon sperm, has been reported to exert anti-inflammatory and anti-ischemic effects through the adenosine A2A receptor (A2AR). We investigated whether PDRN posse...

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Bibliographic Details
Main Authors: Sung-Eun Kim, Il-Gyu Ko, Jun-Jang Jin, Lakkyong Hwang, Chang-Ju Kim, Sang-Hoon Kim, Jin-Hee Han, Jung Won Jeon
Format: Article
Language:English
Published: Hindawi Limited 2020-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2020/2169083