18q loss of heterozygosity in microsatellite stable colorectal cancer is correlated with CpG island methylator phenotype-negative (CIMP-0) and inversely with CIMP-low and CIMP-high

<p>Abstract</p> <p>Background:</p> <p>The CpG island methylator phenotype (CIMP) with widespread promoter methylation is a distinct epigenetic phenotype in colorectal cancer, associated with microsatellite instability-high (MSI-high) and <it>BRAF </it>mutati...

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Bibliographic Details
Main Authors: Kirkner Gregory J, Kawasaki Takako, Ogino Shuji, Ohnishi Mutsuko, Fuchs Charles S
Format: Article
Language:English
Published: BMC 2007-05-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/7/72