ABCG1 regulates pulmonary surfactant metabolism in mice and men[S]

ABCG1 regulates pulmonary surfactant metabolism in mice and men[S]

Idiopathic pulmonary alveolar proteinosis (PAP) is a rare lung disease characterized by accumulation of surfactant. Surfactant synthesis and secretion are restricted to epithelial type 2 (T2) pneumocytes (also called T2 cells). Clearance of surfactant is dependent upon T2 cells and macrophages. ABCG...

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Bibliographic Details
Main Authors: Thomas Q. de Aguiar Vallim, Elinor Lee, David J. Merriott, Christopher N. Goulbourne, Joan Cheng, Angela Cheng, Ayelet Gonen, Ryan M. Allen, Elisa N.D. Palladino, David A. Ford, Tisha Wang, Ángel Baldán, Elizabeth J. Tarling
Format: Article
Language:English
Published: Elsevier 2017-05-01
Series:Journal of Lipid Research
Subjects:
cholesterol
phospholipid
lung
pulmonary alveolar proteinosis
ATP binding cassette transporter G1
Online Access:http://www.sciencedirect.com/science/article/pii/S002222752033830X

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http://www.sciencedirect.com/science/article/pii/S002222752033830X

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