Dynamic mechanism of multiple bursting patterns in a whole-cell multiscale model with calcium oscillations
The dynamic mechanism of a whole-cell model containing electrical signalling and two-compartment Ca $ ^{2+} $ signalling in gonadotrophs is investigated. The transition from spiking to bursting by Hopf bifurcation of the fast subsystem about the slow variable is detected via the suitable parameters....
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Taylor & Francis Group
2021-01-01
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Series: | Journal of Biological Dynamics |
Subjects: | |
Online Access: | http://dx.doi.org/10.1080/17513758.2021.1925753 |