Chaenomelis fructus inhibits osteoclast differentiation by suppressing NFATc1 expression and prevents ovariectomy-induced osteoporosis

Abstract Background Osteoporosis is related to the number and activity of osteoclasts. The goal of the present study was to demonstrate the effect of Chaenomelis Fructus (CF) on osteoclastogenesis and its mechanism of bone loss prevention in an OVX-induced osteoporosis model. Methods Osteoclasts wer...

Full description

Bibliographic Details
Main Authors: Minsun Kim, Ho-Seok Kim, Jae-Hyun Kim, Eun-Young Kim, Bina Lee, Sung Yub Lee, Jae-Yun Jun, Min Beom Kim, Youngjoo Sohn, Hyuk-Sang Jung
Format: Article
Language:English
Published: BMC 2020-02-01
Series:BMC Complementary Medicine and Therapies
Subjects:
Online Access:https://doi.org/10.1186/s12906-020-2841-9