Use it or lose it: establishment and persistence of T cell memory

Pre-existing T cell memory provides substantial protection against viral, bacterial and parasitic infections. The generation of protective T cell memory constitutes a primary goal for cell-mediated vaccines, thus understanding the mechanistic basis of memory development and maintenance are of major...

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Bibliographic Details
Main Authors: Katherine eKedzierska, Sophie eValkenburg, Peter eDoherty, Miles eDavenport, Vanessa eVenturi
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-11-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2012.00357/full