Integrated bioinformatics analysis of the crucial candidate genes and pathways associated with glucocorticoid resistance in acute lymphoblastic leukemia

Integrated bioinformatics analysis of the crucial candidate genes and pathways associated with glucocorticoid resistance in acute lymphoblastic leukemia

Abstract Glucocorticoids (GC) are the foundation of the chemotherapy regimen in acute lymphoblastic leukemia (ALL). However, resistance to GC is observed more frequently than resistance to other chemotherapy agents in patients with ALL relapse. Moreover, the mechanism underlying the development of G...

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Bibliographic Details
Main Authors: Yanxin Chen, Peifang Jiang, Jingjing Wen, Zhengjun Wu, Jiazheng Li, Yuwen Chen, Lingyan Wang, Donghui Gan, Yingyu Chen, Ting Yang, Minhui Lin, Jianda Hu
Format: Article
Language:English
Published: Wiley 2020-04-01
Series:Cancer Medicine
Subjects:
acute lymphoblastic leukemia
bioinformatic analysis
glucocorticoid resistance
MYC
signaling pathway
Online Access:https://doi.org/10.1002/cam4.2934

Internet

https://doi.org/10.1002/cam4.2934

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