Interleukin-4 Receptor Alpha Expressing B Cells Are Essential to Down-Modulate Host Granulomatous Inflammation During Schistosomasis

Interleukin-4 Receptor Alpha Expressing B Cells Are Essential to Down-Modulate Host Granulomatous Inflammation During Schistosomasis

Schistosomiasis (bilharzia) is a parasitic helminth disease that can cause severe inflammatory pathology leading to organ damage in humans. Failure of the host to regulate egg-driven granulomatous inflammation causes host morbidity during chronic infection with Schistosoma mansoni. Although the impo...

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Bibliographic Details
Main Authors: Hlumani Ndlovu, Justin Komguep Nono, Nada Abdel Aziz, Natalie Eva Nieuwenhuizen, Frank Brombacher
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-12-01
Series:Frontiers in Immunology
Subjects:
schistosomiais
B cells
pathology
IL-4RA
chronic infection
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.02928/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2018.02928/full

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