Differentially Tolerized Mouse Antigen Presenting Cells Share a Common miRNA Signature Including Enhanced mmu-miR-223-3p Expression Which Is Sufficient to Imprint a Protolerogenic State

Differentially Tolerized Mouse Antigen Presenting Cells Share a Common miRNA Signature Including Enhanced mmu-miR-223-3p Expression Which Is Sufficient to Imprint a Protolerogenic State

Dendritic cells (DCs) are pivotal for the induction and maintenance of antigen-specific tolerance and immunity. miRNAs mediate post-transcriptional gene regulation and control in part the differentiation and stimulation-induced immunogenic function of DCs. However, the relevance of miRNAs for the in...

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Bibliographic Details
Main Authors: Matthias Bros, Mahmoud Youns, Verena Kollek, Diana Buchmüller, Franziska Bollmann, Ean-Jeong Seo, Jonathan Schupp, Evelyn Montermann, Svetlana Usanova, Hartmut Kleinert, Thomas Efferth, Angelika B. Reske-Kunz
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-08-01
Series:Frontiers in Pharmacology
Subjects:
dexamethasone
interleukin-10
miRNA
mmu-miR-223-3p
tolerogenic dendritic cells
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2018.00915/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2018.00915/full

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