Effects of hemochromatosis and transferrin gene mutations on peripheral iron dyshomeostasis in Mild Cognitive Impairment and Alzheimer’s and Parkinson’s diseases

Effects of hemochromatosis and transferrin gene mutations on peripheral iron dyshomeostasis in Mild Cognitive Impairment and Alzheimer’s and Parkinson’s diseases

Deregulation of iron metabolism has been observed in patients with neurodegenerative diseases. We have carried out a molecular analysis investigating the interaction between iron specific gene variants [transferrin (TF, P589S), hemochromatosis (HFE) C282Y and H63D)], iron biochemical variables [iron...

Full description

Bibliographic Details
Main Authors: Stefania eMariani, Mariacarla eVentriglia, Ilaria eSimonelli, Gianfranco eSpalletta, Francesca eAssogna, Serena eBucossi, Mariacristina eSiotto, Jean-Marc eMelgari, Fabrizio eVernieri, Rosanna eSquitti
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-08-01
Series:Frontiers in Aging Neuroscience
Subjects:
Iron
Transferrin
Parkinson’s disease
Alzheimer’s disease
HFE
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnagi.2013.00037/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnagi.2013.00037/full

Similar Items