Metalloproteins during development of Walker-256 carcinosarcoma resistant phenotype

Metalloproteins during development of Walker-256 carcinosarcoma resistant phenotype

The study was focused on the detection of changes in serum and tumor metal-containing proteins in animals during development of doxorubicin-resistant phenotype in malignant cells after 12 courses of chemotherapy. We found that on every stage of resistance development there was a significant increase...

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Bibliographic Details
Main Authors: V. F. Chekhun, Yu. V. Lozovska, A. P. Burlaka, I. I. Ganusevich, Yu. V. Shvets, N. Yu. Lukianova, I. M. Todor, D. V. Demash, A. A. Pavlova, L. A. Naleskina
Format: Article
Language:English
Published: National Academy of Sciences of Ukraine and Palladin Institute of Biochemistry of the National Academy of Sciences of Ukraine. 2015-04-01
Series:Ukrainian Biochemical Journal
Subjects:
ceruloplasmin
doxorubicin
ferritin
MMP-2 and MMP-9
reactive oxygen species
thiol groups
transferrin
Walker-256 carcinosarcoma
‘free iron’ complexes
Online Access:http://ukrbiochemjournal.org/wp-content/uploads/2015/05/Chekhun_2_15.pdf

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http://ukrbiochemjournal.org/wp-content/uploads/2015/05/Chekhun_2_15.pdf

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