Topological Bias in Distance-Based Phylogenetic Methods: Problems with Over- and Underestimated Genetic Distances

Topological Bias in Distance-Based Phylogenetic Methods: Problems with Over- and Underestimated Genetic Distances

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I show several types of topological biases in distance-based methods that use the least-squares method to evaluate branch lengths and the minimum evolution (ME) or the Fitch-Margoliash (FM) criterion to choose the best tree. For a 6-species tree, there are two tree shapes, one with three cherries (a...

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Bibliographic Details
Main Author: Xuhua Xia
Format: Article
Language:English
Published: SAGE Publishing 2006-01-01
Series:Evolutionary Bioinformatics
Subjects:
topological bias
minimum evolution
least-squares method
Fitch-Margoliash
Online Access:http://la-press.com/article.php?article_id=124

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http://la-press.com/article.php?article_id=124

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