Investigating the Transition of Pre-Symptomatic to Symptomatic Huntington’s Disease Status Based on Omics Data

Investigating the Transition of Pre-Symptomatic to Symptomatic Huntington’s Disease Status Based on Omics Data

Huntington’s disease is a rare neurodegenerative disease caused by a cytosine–adenine–guanine (CAG) trinucleotide expansion in the Huntingtin (<i>HTT</i>) gene. Although Huntington’s disease (HD) is well studied, the pathophysiological mechanisms, genes and metabolites involved in HD rem...

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Bibliographic Details
Main Authors: Christiana C. Christodoulou, Margarita Zachariou, Marios Tomazou, Evangelos Karatzas, Christiana A. Demetriou, Eleni Zamba-Papanicolaou, George M. Spyrou
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:International Journal of Molecular Sciences
Subjects:
huntington’s disease
systems bioinformatics
pathways
metabolites
gene co-expression
network biology
Online Access:https://www.mdpi.com/1422-0067/21/19/7414

Internet

https://www.mdpi.com/1422-0067/21/19/7414

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