A mathematical model explains saturating axon guidance responses to molecular gradients
Correct wiring is crucial for the proper functioning of the nervous system. Molecular gradients provide critical signals to guide growth cones, which are the motile tips of developing axons, to their targets. However, in vitro, growth cones trace highly stochastic trajectories, and exactly how molec...
Main Authors: | , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2016-02-01
|
Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/12248 |