Global estrogen receptor-α knockout has differential effects on cortical and cancellous bone in aged male mice
Estrogen receptor-α knockout (ERKO) in female rodents results in bone loss associated with increased osteocyte sclerostin expression; whether this also occurs in males is unknown. Here, we examined the effects of ERKO on femoral cortical geometry, trabecular microarchitecture, and osteocyte sclerost...
Main Authors: | , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Canadian Science Publishing
2020-05-01
|
Series: | FACETS |
Subjects: | |
Online Access: | https://www.facetsjournal.com/doi/full/10.1139/facets-2019-0043 |