Antiproliferative and antimetastatic characterization of an exo-heterocyclic androstane derivative against human breast cancer cell lines

Cancer in general, and specifically gynaecological neoplasms, represents a major public health issue worldwide. Based on the effect of sex hormones on breast tumorigenesis and prognosis, as well as on the development of breast cancer metastases, modification of the steroid skeleton is a hotspot of r...

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Bibliographic Details
Main Authors: Ágnes E. Kulmány, Éva Frank, Dóra Kovács, Kerstin Kirisits, Georg Krupitza, Patrícia Neuperger, Róbert Alföldi, László G. Puskás, Gábor J. Szebeni, István Zupkó
Format: Article
Language:English
Published: Elsevier 2021-08-01
Series:Biomedicine & Pharmacotherapy
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Online Access:http://www.sciencedirect.com/science/article/pii/S0753332221005102