Acetylcorynoline impairs the maturation of mouse bone marrow-derived dendritic cells via suppression of IκB kinase and mitogen-activated protein kinase activities.

<h4>Background</h4>Dendritic cells (DCs) are major modulators in the immune system. One active field of research is the manipulation of DCs as pharmacological targets to screen novel biological modifiers for the treatment of inflammatory and autoimmune disorders. Acetylcorynoline is the...

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Main Authors: Ru-Huei Fu, Yu-Chi Wang, Shih-Ping Liu, Ching-Liang Chu, Rong-Tzong Tsai, Yu-Chen Ho, Wen-Lin Chang, Shao-Chih Chiu, Horng-Jyh Harn, Woei-Cherng Shyu, Shinn-Zong Lin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23472193/pdf/?tool=EBI