Neurological complications of immune checkpoint inhibitors: what happens when you ‘take the brakes off’ the immune system

Patients with advanced malignancies treated with immune checkpoint inhibitors are at increased risk for developing immune-related neurological complications. It is a phenomenon of immunological twist when immunotherapy against co-stimulatory molecules activates previously normal T cells to kill tumo...

Full description

Bibliographic Details
Main Author: Marinos C. Dalakas
Format: Article
Language:English
Published: SAGE Publishing 2018-09-01
Series:Therapeutic Advances in Neurological Disorders
Online Access:https://doi.org/10.1177/1756286418799864