Snai1 represses Nanog to promote embryonic stem cell differentiation

Embryonic stem cell (ESC) self-renewal and pluripotency is maintained by an external signaling pathways and intrinsic regulatory networks involving ESC-specific transcriptional complexes (mainly formed by OCT3/4, Sox2 and Nanog proteins), the Polycomb repressive complex 2 (PRC2) and DNA methylation...

Full description

Bibliographic Details
Main Authors: F. Galvagni, F. Neri
Format: Article
Language:English
Published: Elsevier 2015-06-01
Series:Genomics Data
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2213596015000240