Proteomics reveals the function reverse of MPSSS‐treated prostate cancer‐associated fibroblasts to suppress PC‐3 cell viability via the FoxO pathway

Proteomics reveals the function reverse of MPSSS‐treated prostate cancer‐associated fibroblasts to suppress PC‐3 cell viability via the FoxO pathway

Abstract Prostate cancer‐associated fibroblasts (prostate CAFs) are essential components of the tumor microenvironment and can promote tumor progression through their immunosuppressive functions. MPSSS, a novel polysaccharide purified from Lentinus edodes, has been reported to have anti‐tumor activi...

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Bibliographic Details
Main Authors: Tingting Zhang, Xiulan Chen, Lang Sun, Xiaojing Guo, Tanxi Cai, Jifeng Wang, Yanqiong Zeng, Jing Ma, Xiang Ding, Zhensheng Xie, Lili Niu, Mengmeng Zhang, Ning Tao, Fuquan Yang
Format: Article
Language:English
Published: Wiley 2021-04-01
Series:Cancer Medicine
Subjects:
cell cycle arrest
MPSSS
quantitative proteomics
TGF‐β3
the FoxO pathway
Online Access:https://doi.org/10.1002/cam4.3825

Internet

https://doi.org/10.1002/cam4.3825

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