Investigating the Pathogenic Role of PADI4 in Oesophageal Cancer

<p>PADI4 post-translationally converts peptidylarginine to citrulline. PADI4 can disrupt the apoptotic process via the citrullination of histone H3 in the promoter of p53-target genes. The current study focused on PADI4 expression in various subtypes of oesophageal carcinoma (EC) by immunohist...

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Bibliographic Details
Main Author: Xiaotian Chang, Xiuli Hou, Jihong Pan, Kehua Fang, Lin Wang, Jinxiang Han
Format: Article
Language:English
Published: Ivyspring International Publisher 2011-01-01
Series:International Journal of Biological Sciences
Online Access:http://www.biolsci.org/v07p0769.htm