The regulation of DNA damage tolerance by Ubiquitin and Ubiquitin-like modifiers

The regulation of DNA damage tolerance by Ubiquitin and Ubiquitin-like modifiers

DNA replication is an extremely complex process that needs to be executed in a highly accurate manner in order to propagate the genome. This task requires the coordination of a number of enzymatic activities and it is incredibly fragile and prone to arrest after DNA damage. DNA damage tolerance prov...

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Bibliographic Details
Main Authors: Lina Cipolla, Antonio Maffia, Federica Bertoletti, Simone Sabbioneda
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-06-01
Series:Frontiers in Genetics
Subjects:
Sumoylation
ubiquitylation
PCNA
Isgylation
Translesion Synthesis
DNA damage tolerance
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2016.00105/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fgene.2016.00105/full

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