Aurora-A Kinase as a Promising Therapeutic Target in Cancer

Mammalian Aurora family of serine/threonine kinases are master regulators of mitotic progression and are frequently overexpressed in human cancers. Among the three members of the Aurora kinase family (Aurora-A, -B and –C), Aurora-A and Aurora-B are expressed at detectable levels in somatic cells und...

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Bibliographic Details
Main Authors: Antonio B D'Assoro, Tufia eHaddad, Evanthia eGalanis
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-01-01
Series:Frontiers in Oncology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fonc.2015.00295/full