Nephroprotective effect of heparanase in experimental nephrotic syndrome.

Heparanase, an endoglycosidase that cleaves heparan sulfate (HS), is involved in various biologic processes. Recently, an association between heparanase and glomerular injury was suggested. The present study examines the involvement of heparanase in the pathogenesis of Adriamycin-induced nephrotic s...

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Bibliographic Details
Main Authors: Suheir Assady, Joel Alter, Elena Axelman, Yaniv Zohar, Edmond Sabo, Michael Litvak, Marielle Kaplan, Neta Ilan, Israel Vlodavsky, Zaid Abassi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4364762?pdf=render