Enantiopure Indolo[2,3-a]quinolizidines: Synthesis and Evaluation as NMDA Receptor Antagonists

Enantiopure tryptophanol is easily obtained from the reduction of its parent natural amino acid trypthophan (available from the chiral pool), and can be used as chiral auxiliary/inductor to control the stereochemical course of a diastereoselective reaction. Furthermore, enantiopure tryptophanol is u...

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Bibliographic Details
Main Authors: Nuno A. L. Pereira, Francesc X. Sureda, Maria Pérez, Mercedes Amat, Maria M. M. Santos
Format: Article
Language:English
Published: MDPI AG 2016-08-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/21/8/1027