Epigenetic Rejuvenation of Mesenchymal Stromal Cells Derived from Induced Pluripotent Stem Cells

Standardization of mesenchymal stromal cells (MSCs) remains a major obstacle in regenerative medicine. Starting material and culture expansion affect cell preparations and render comparison between studies difficult. In contrast, induced pluripotent stem cells (iPSCs) assimilate toward a ground stat...

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Bibliographic Details
Main Authors: Joana Frobel, Hatim Hemeda, Michael Lenz, Giulio Abagnale, Sylvia Joussen, Bernd Denecke, Tomo Šarić, Martin Zenke, Wolfgang Wagner
Format: Article
Language:English
Published: Elsevier 2014-09-01
Series:Stem Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671114002331