Synergistic and non-specific nucleic acid production by T7 RNA polymerase and Bsu DNA polymerase catalyzed by single-stranded polynucleotides

Point-of-care molecular diagnostic tests show great promise for providing accurate, timely results in low-infrastructure healthcare settings and at home. The design space for these tests is limited by a variety of possible background reactions, which often originate from relatively weak promiscuous...

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Bibliographic Details
Main Authors: Nicholas J. Emery, Sagardip Majumder, Allen P. Liu
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2018-06-01
Series:Synthetic and Systems Biotechnology
Online Access:http://www.sciencedirect.com/science/article/pii/S2405805X17301096