Topological structure of the space of phenotypes: the case of RNA neutral networks.
The evolution and adaptation of molecular populations is constrained by the diversity accessible through mutational processes. RNA is a paradigmatic example of biopolymer where genotype (sequence) and phenotype (approximated by the secondary structure fold) are identified in a single molecule. The e...
Main Authors: | Jacobo Aguirre, Javier M Buldú, Michael Stich, Susanna C Manrubia |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2011-01-01
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Series: | PLoS ONE |
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22028856/?tool=EBI |
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