Intermittent High Glucose Enhances the Proliferation of Rat Aortic Vascular Smooth Muscle Cells More Than Constant High Glucose via the Mitogen-Activated Protein Kinase Pathway

Intermittent High Glucose Enhances the Proliferation of Rat Aortic Vascular Smooth Muscle Cells More Than Constant High Glucose via the Mitogen-Activated Protein Kinase Pathway

Background : The acute glucose fluctuations in diabetes can be a risk factor of cardiovascular events. Nonetheless, the mechanism of action of intermittent hyperglycemia on the proliferation of vascular smooth muscle cells (VSMCs) is poorly understood. We compared the effects of exposure to constant...

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Bibliographic Details
Main Authors: Sung Hoon Yu, Hyung Joon Yoo, Dong Hyun Kang, Shin Je Moon, Jae Myung Yu
Format: Article
Language:English
Published: Korea Geriatrics Society 2017-09-01
Series:Annals of Geriatric Medicine and Research
Subjects:
Intermittent high glucose
Vascular smooth muscle cell
Mitogen-activated protein kinase
Apoptosis
Online Access:http://www.e-agmr.org/journal/view.html?doi=10.4235/agmr.2017.21.3.131

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http://www.e-agmr.org/journal/view.html?doi=10.4235/agmr.2017.21.3.131

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