Helper Innate Lymphoid Cells in Human Tumors: A Double-Edged Sword?

Helper Innate Lymphoid Cells in Human Tumors: A Double-Edged Sword?

Innate lymphoid cells (ILCs) were found to be developmentally related to natural killer (NK) cells. In humans, they are mostly located in “barrier” tissues where they contribute to innate defenses against different pathogens. ILCs are heterogeneous and characterized by a high degree of plasticity. I...

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Bibliographic Details
Main Authors: Nicola Tumino, Paola Vacca, Linda Quatrini, Enrico Munari, Francesca Moretta, Andrea Pelosi, Francesca Romana Mariotti, Lorenzo Moretta
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-01-01
Series:Frontiers in Immunology
Subjects:
innate lymphoid cells
antitumor immune response
checkpoint inhibitors
natural killer cells
immunotherapy
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.03140/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.03140/full

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