Mechanical positioning of multiple nuclei in muscle cells.

Many types of large cells have multiple nuclei. In skeletal muscle fibers, the nuclei are distributed along the cell to maximize their internuclear distances. This myonuclear positioning is crucial for cell function. Although microtubules, microtubule associated proteins, and motors have been implic...

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Bibliographic Details
Main Authors: Angelika Manhart, Stefanie Windner, Mary Baylies, Alex Mogilner
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-06-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC6013246?pdf=render