Long-term vector integration site analysis following retroviral mediated gene transfer to hematopoietic stem cells for the treatment of HIV infection.

Long-term vector integration site analysis following retroviral mediated gene transfer to hematopoietic stem cells for the treatment of HIV infection.

We previously reported the efficacy of nonmyeloablative allogeneic transplantation in 2 HIV positive recipients, one of whom received retrovirus transduced hematopoietic stem cells to confer resistance to HIV. Here we report an assessment of retroviral integration sites (RISs) recovered out to 3 yea...

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Bibliographic Details
Main Authors: Jun Hayakawa, Kareem Washington, Naoya Uchida, Oswald Phang, Elizabeth M Kang, Matthew M Hsieh, John F Tisdale
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2615408?pdf=render

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http://europepmc.org/articles/PMC2615408?pdf=render

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