Docking-Guided 3D-QSAR Studies of 4-Aminoquinoline-1,3,5-triazines as Inhibitors for <i>Plasmodium falciparum</i> Dihydrofolate Reductase

Docking-Guided 3D-QSAR Studies of 4-Aminoquinoline-1,3,5-triazines as Inhibitors for <i>Plasmodium falciparum</i> Dihydrofolate Reductase

Mutations in Plasmodium falciparum dihydrofolate reductase (PfDHFR), together with other mutations, hinder malaria elimination in Southeast Asia due to multiple drug resistance. In this article, molecular docking-guided three-dimensional (3D) quantitative structure-activity relationship (QSAR) analy...

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Bibliographic Details
Main Authors: Radite Yogaswara, Maria Ludya Pulung, Sri Hartati Yuliani, Enade Perdana Istyastono
Format: Article
Language:English
Published: Universitas Gadjah Mada 2020-05-01
Series:Indonesian Journal of Chemistry
Subjects:
plasmodium falciparum dihydrofolate reductase
3d-qsar
molecular docking
multiple drug resistance
Online Access:https://jurnal.ugm.ac.id/ijc/article/view/50674

Internet

https://jurnal.ugm.ac.id/ijc/article/view/50674

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