Genetic susceptibility to angiotensin-converting enzyme-inhibitor induced angioedema: A systematic review and evaluation of methodological approaches.

Genetic susceptibility to angiotensin-converting enzyme-inhibitor induced angioedema: A systematic review and evaluation of methodological approaches.

Angiotensin-converting enzyme (ACE) converts angiotensin I to angiotensin II which causes vasoconstriction. ACE inhibitors reduce blood pressure by inhibiting ACE. A well-known adverse drug reaction to ACE inhibitors is ACE inhibitor-induced angioedema (ACEi-AE). Angioedema is a swelling of skin and...

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Bibliographic Details
Main Authors: Haivin Aziz Ali, Anne Fog Lomholt, Seyed Hamidreza Mahmoudpour, Thorbjørn Hermanrud, Anette Bygum, Christian von Buchwald, Marianne Antonius Jakobsen, Eva Rye Rasmussen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0224858

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https://doi.org/10.1371/journal.pone.0224858

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