Protein redox chemistry: post-translational cysteine modifications that regulate signal transduction and drug pharmacology

The perception of reactive oxygen species (ROS) has evolved over the past decade from agents of cellular damage to secondary messengers which modify signaling proteins in physiology and the disease state (e.g. cancer). New protein targets of specific oxidation are rapidly being identified. One eme...

Full description

Bibliographic Details
Main Authors: Revati eWani, Asako eNagata, Brion William Murray
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-10-01
Series:Frontiers in Pharmacology
Subjects:
ROS
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2014.00224/full