Puerarin ameliorated the behavioral deficits induced by chronic stress in rats

Abstract The present study aimed to investigate the mechanisms underlying the antidepressant-like effects of puerarin via the chronic unpredictable stress (CUS) procedure in rats. Similar to Sertraline (Ser), Chronic treatment of puerarin (60 and 120 mg/kg, i.g) elicited the antidepressant-like effe...

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Bibliographic Details
Main Authors: Zhi-Kun Qiu, Guan-Hua Zhang, De-Sheng Zhong, Jia-Li He, Xu Liu, Ji-Sheng Chen, Da-Nian Wei
Format: Article
Language:English
Published: Nature Publishing Group 2017-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-06552-x