The AP-1 binding sites located in the pol gene intragenic regulatory region of HIV-1 are important for viral replication.

Our laboratory has previously identified an important intragenic region in the human immunodeficiency virus type 1 (HIV-1) genome, whose complete functional unit is composed of the 5103 fragment, the DNaseI-hypersensitive site HS7 and the 5105 fragment. These fragments (5103 and 5105) both exhibit a...

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Bibliographic Details
Main Authors: Laurence Colin, Nathalie Vandenhoudt, Stéphane de Walque, Benoît Van Driessche, Anna Bergamaschi, Valérie Martinelli, Thomas Cherrier, Caroline Vanhulle, Allan Guiguen, Annie David, Arsène Burny, Georges Herbein, Gianfranco Pancino, Olivier Rohr, Carine Van Lint
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3079759?pdf=render