New evidence from plasma ceramides links apoE polymorphism to greater risk of coronary artery disease in Finnish adults[S]

New evidence from plasma ceramides links apoE polymorphism to greater risk of coronary artery disease in Finnish adults[S]

apoE, a key regulator of plasma lipids, mediates altered functionalities in lipoprotein metabolism and thus affects the risk of coronary artery disease (CAD). The significance of different apoE polymorphisms remains unclear; although the ε4 allele is clearly associated with increased cholesterol lev...

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Bibliographic Details
Main Authors: Juho-Pekka Karjalainen, Nina Mononen, Nina Hutri-Kähönen, Miikael Lehtimäki, Mika Hilvo, Dimple Kauhanen, Markus Juonala, Jorma Viikari, Mika Kähönen, Olli Raitakari, Reijo Laaksonen, Terho Lehtimäki
Format: Article
Language:English
Published: Elsevier 2019-09-01
Series:Journal of Lipid Research
Subjects:
apolipoprotein E
atherosclerosis
dyslipidemias
genes
lipid dysfunction
low-density lipoprotein
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520323233

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http://www.sciencedirect.com/science/article/pii/S0022227520323233

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