Interactions between the Hepatitis C Virus Nonstructural 2 Protein and Host Adaptor Proteins 1 and 4 Orchestrate Virus Release

Interactions between the Hepatitis C Virus Nonstructural 2 Protein and Host Adaptor Proteins 1 and 4 Orchestrate Virus Release

Hepatitis C virus (HCV) spreads via secreted cell-free particles or direct cell-to-cell transmission. Yet, virus-host determinants governing differential intracellular trafficking of cell-free- and cell-to-cell-transmitted virus remain unknown. The host adaptor proteins (APs) AP-1A, AP-1B, and AP-4...

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Bibliographic Details
Main Authors: Fei Xiao, Stanley Wang, Rina Barouch-Bentov, Gregory Neveu, Szuyuan Pu, Melanie Beer, Stanford Schor, Sathish Kumar, Vlad Nicolaescu, Brett D. Lindenbach, Glenn Randall, Shirit Einav, Thomas Pietschmann, Diane E. Griffin
Format: Article
Language:English
Published: American Society for Microbiology 2018-03-01
Series:mBio
Online Access:http://mbio.asm.org/cgi/content/full/9/2/e02233-17

Internet

http://mbio.asm.org/cgi/content/full/9/2/e02233-17

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