Identification of active <it>Plasmodium falciparum</it> calpain to establish screening system for <it>Pf</it>-calpain-based drug development

Identification of active <it>Plasmodium falciparum</it> calpain to establish screening system for <it>Pf</it>-calpain-based drug development

<p>Abstract</p> <p>Background</p> <p>With the increasing resistance of malaria parasites to available drugs, there is an urgent demand to develop new anti-malarial drugs. Calpain inhibitor, ALLN, is proposed to inhibit parasite proliferation by suppressing haemoglobin d...

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Bibliographic Details
Main Authors: Soh Byoung, Song Hyun-Ok, Lee Yoonji, Lee Junghyun, Kaewintajuk Kusuma, Lee Binna, Choi Yun-Young, Cho Jeong, Choi Sun, Park Hyun
Format: Article
Language:English
Published: BMC 2013-02-01
Series:Malaria Journal
Subjects:
Calpain
Malaria
<it>Plasmodium falciparum</it>
Monomer
Cysteine protease
Protease inhibitor
Anti-malarial drug
Online Access:http://www.malariajournal.com/content/12/1/47

Internet

http://www.malariajournal.com/content/12/1/47

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