The Brain Renin-Angiotensin System and Mitochondrial Function: Influence on Blood Pressure and Baroreflex in Transgenic Rat Strains

Mitochondrial dysfunction is implicated in many cardiovascular diseases, including hypertension, and may be associated with an overactive renin-angiotensin system (RAS). Angiotensin (Ang) II, a potent vasoconstrictor hormone of the RAS, also impairs baroreflex and mitochondrial function. Most delete...

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Bibliographic Details
Main Authors: Manisha Nautiyal, Amy C. Arnold, Mark C. Chappell, Debra I. Diz
Format: Article
Language:English
Published: Hindawi Limited 2013-01-01
Series:International Journal of Hypertension
Online Access:http://dx.doi.org/10.1155/2013/136028